Stereology shows that damaged liver recovers after protein refeeding
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چکیده
منابع مشابه
Inhomogeneity of liver glycogen synthesis upon refeeding after starvation.
Normal hepatic glycogen levels are in the range 300-400 pmol/g of tissue wet weight [ 11. Starvation for periods longer than 12 h severely depletes the hepatic glycogen store, as it is rapidly mobilized to provide glucose for extrahepatic tissue metabolism [ 11. Typical levels remaining after mild starvation of 24-48 h are reported as being less than 40 pmol/g of tissue wet weight for the rat a...
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definition of some external characteristics used in the assessment of gestational age in the newborn infant. Sir, Dugdale et al.1 compared the results obtained in two groups of infants suffering from acute diarrhoea who were submitted to either a rapid or a graduated refeeding regimen, and concluded that weight loss during the first 24 hours of refeeding was less and the length of hospital stay...
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Hypothyroidism is a growing medical concern. There are conflicting reports regarding the mechanism of oxidative stress in hypothyroidism. Mitochondrial oxidative stress is pivotal to thyroid dysfunction. The present study aimed to delineate the effects of hepatic inner mitochondrial membrane dysfunction as a consequence of 6-n-propyl-2-thiouracil-induced hypothyroidism in rats. Increased oxidat...
متن کاملStereology.
1.1 組織標本を使用する定量解析が抱える諸問題 組織標本の解析は定性的な所見から始まる.顕微鏡を用いた丁寧な観察によって初めて得られる検体の 大きさや分布,形態などについての詳細な情報は,全ての研究の基礎となるべき重要なものである.しか しながら,定性的なデータだけでは,統計学的な検討が難しく,結果が主観的なものになりやすい.この ため,生理的組織と病的組織の比較など,さらなる研究を行う際には,定量的なデータが必要になる.定 量解析の基本的な命題は,いかにして検体の正確な数を客観的に求めることができるか,ということであ る.組織標本に基づく定量解析は単純に思われるが,正確なデータを得ることは実は容易ではない. 最大の問題は,サンプリングバイアスである(図1).これは,標本抽出の際に母集団を代表していない 検体が選ばれるために生じる偏りのことであり,2次元的な切片を使って定量解析を行...
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The role of IL-7 during thymopoiesis has led to it being the focus of a number of therapeutic interventions. However, its small size and pleiotropic nature present problems for thymus-directed therapies. We have created a fusion molecule between the extracellular N-terminal domain of CCR9 and IL-7, which has the potential to overcome these difficulties. This novel fusion protein retains the thy...
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ژورنال
عنوان ژورنال: Nutrition
سال: 2017
ISSN: 0899-9007
DOI: 10.1016/j.nut.2017.02.010